Are you a type 2 diabetic and treated with pioglitazone? Do you know, up to 75 percent of the increase in body weight that can occur in is from you water retention? Researchers reported this in the journal Diabetes Care. The drug also tends to reduce abdominal fat and blood pressure. Sold in the US under the trade name Metaglip, pioglitazone is sold under the trade name Actos and glipizide. Dr. Ananda Basu and colleagues at the Mayo Clinic Rochester, Minnesota compared the effects of the drug on body composition and body water content, as well as other factors, in 19 patients with type 2 diabetes. Though pioglitazone tended to reduce the average blood pressure, glipizide had no impact on blood pressure.
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